I will try to mentione a few important for those who are sitting for MRCP soon.
Multiple sclerosis is an autoimmune demyelinating disease affecting the central nervous system-brain and the spinal cord.
Since Mutiple Sclerosis ( MS) can affect any part in the central nervous system, patients with MS can present in diverse ways. However, 2 clincal syndromes that are popular in MRCP is acute transverse myelitis and Optic neuritis.
Patients with acute transverse myelitis usually have acute paralysis of lower limbs with sensory level ( upper motor neuron signs) with or without autonomic symptoms- urinary/bowel incontinence.
For patients with Optic neuritis, usually one eye is involved and patients may get blurring of vision or even visual loss!
For you to diagnose MS, you can follow the Poser criteria. You can click here to learn more. For you, I think you need to remember only this - you need 2 sites ( central nervous system) involvement at 2 different times ( 2 attacks) to make the diagnosis.
MRI is always helpful in making the diagnosis.
As for the treatment, I think you just need to remember one of them is interferon!
3 comments:
can u explain more bout devic disease and INO? thx a lot
Thanks for giving such useful information about MRCP. I want to know more about the MRCP paces examination.
Multiple Sclerosis is the disease which affects the spinal cord and brain. This may lead to problems in vision, muscle control and sensation. The immune system affects the brain and spinal cord and also builds up the scar tissue called sclerosis. This scar tissue is developed during demyelination. MRCP Courses UK
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