In my last post, I talk about iron metabolism in MRCP, as you all know, iron is an important ingredient in heme synthesis. Therefore iron deficiency leads to anemia ( hypochromic,microcystic anemia) which is a type of anemia manifested by small red cells ( low MCV- mean corpuscular volume) and pale red blood cells ( low MCHC- mean cospuscular hemoglobin concentration).
Iron deficiency is diagnosed by diagnostic tests as a low serum ferritin, a low serum iron level, an elevated serum transferin and a high total iron binding capacity (TIBC).
So what causes iron deficiency anemia- yes, it is mainly due to chronic blood loss and the main cause worldwide is worms infestations! (hookworms, whipworms, roundworms). However, another reason for chronic blood loss is GIT bleeding, therefore, for anyone older than 50 years, always think of the possibility of GIT malignancy!
One thing to take note, Thalassemia minor also has the similar lab results as iron deficiency and you must always consider Thalassemia as your differential diagnosis in iron deficiency anemia!
2 comments:
sometimes when u sent the blood for investigation in case of anemia, the result comes back as low serum iron and low serum TIBC..
what is ur thought for this?
thx
Aplastic Anemia is the result of the bone marrow not producing enough red blood cells due, possibly, to exposure to toxic chemicals that damage the bone marrow. Without treatment the condition can be fatal. There are treatments available to assist the patient with this disorder.
Exhilarin Adrenogen
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