As in my previous posts, I have discussed 3 most popular drugs in MRCP ie warfarin, digoxin and amiodarone. Today I would talk about antithyroid drugs. There are 2 main antithyroid drugs available namely propylthiouracil (PTU) and methimazole, or carbimazole, a derivative of methimazole which is commonly used in UK and Europe.
Commonly asked questions in MRCP are about the side effects of these drugs, remember that both drugs have quite similar side effects, these side effects are,
a) Rashes
b) Hepatitis and cholestatic jaundice
c) Agranulocytosis ( patients usually present with severe sorethroat!)
Remember and learn how to intepret T4/TSH results after treatment. This is commonly asked in exam as well!
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